Title: Effects of Smoking Cessation on Clincal Symptoms and Respiratory Function in Patients of Different Gender with Chronic Obstructive Pulmonary Disease
Abstract:Objective To investigate the effects of smoking cessation on clinical symptoms and respiratory function of patients of different gender with chronic obstructive pulmonary disease(COPD).Methods A total...Objective To investigate the effects of smoking cessation on clinical symptoms and respiratory function of patients of different gender with chronic obstructive pulmonary disease(COPD).Methods A total of 87 male COPD smokers(male group)and 60 female COPD smokers(female group)who were treated in our pulmonary clinic from December 2008 to November 2010 were enrolled in this study.Both groups were given smoking cessation interventions for one year.The clinical symptoms and respiratory function at presentation and one year later were recorded.The lung function was assessed using FEV1%Pred.Results The success rate of smoking cessation was 40%(35/87)in the male group and 22%(13/60)in the female group(χ2=5.56,P=0.018).The clinical symptom scores and respiratory function between patients who had successfully quit smoking in both groups showed no significant difference at the enrollment(P0.05).One year after intervetnion,the differences became statistically significant(P0.05).In male quitters,the average pulmonary symptom score(2.4±2.5)and respiratory function(3.1±2.2)% were significantly improved when compared with the baseline(t= 6.42,8.51,P0.05).In female quitters,the average change of pulmonary symptoms and respiratory function were(1.0±1.3)and(8.4±1.7)%,which were also significantly improved compared with the baseline(t=2.54,17.6,P0.05).At the enrollment,the clinical symptom score and respiratory function were not significantly different between male and female groups(P0.05);One year later,however,there was a significant difference between them(P0.05).In male smokers,the average change of pulmonary symptom score and respiratory function were(1.1±1.0)and(4.2±3.6)%,respectively,which were also significantly improved when compared with the baseline(t=5.51,8.40,P0.05).In female smokers,the average change of pulmonary symptom score and respiratory function were(2.0±1.4)and(6.8±3.5)%,respectively,which was also significantly improved when compared with the baseline(t=5.53,13.25,P0.05).Conclusion Smoking cessation interventions may improve the clinical symptoms and lung function of smokers with COPD.However,it is somehow more difficult for females to quit smoking.The effectiveness of interventions differs between males and females,and therefore more tailored strategies should be developed to achieve successful smoking cessation.Read More
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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Cited By Count: 1
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