Title: Expression and its clinical significance of RhoC mRNA in human primary hepatocellular carcinoma
Abstract: Objective To study the expression of RhoC mRNA in human primary hepatocellular carcinoma(PHCC) and paracarcinoma liver(PCL) tissues .Method Reverse transcription polymerase chain reaction(RT-PCR) was used to detect the expression of RhoC mRNA in the PHCC and PCL tissue of 30 patients with PHCC. Results The opacity density (OD)of RhoC mRNA expression in PHCC tissues was significantly higher than that in PCL tissures(P0.01);the OD of RhoC mRNA expression in the PHCC with intrahepatic metastasis was significantly higher than that in the PHCC without intrahepatic metastasis(P 0.05). Conclusions The expression of RhoC mRNA in the PHCC is likely related to the metastasis,so that it may act as a good marker for the metastasis of PHCC.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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