Title: Clinical analysis of 32 children with diabetic ketoacidosis as the first symptom of diabetes mellitus
Abstract: Objective To discuss the clinical features, diagnosis and treatment in children with diabetic ketoacidosis (DKA) as the first symptom of diabetes mellitus. Methods Clinical data of 32 children with DKA as the first symptom of diabetes mellitus were investigated retrospectively. Results Twenty-nine patients had clinical features including polydipsia, polyuria and weight loss. There were 16 patients complicated with respiratory tract infection, 1 patient with mumps, 1 patient with urinary tract infection, 2 patients with gastrointestinal infection. Eleven patients had gastrointestinal symptoms of nausea, vomiting and abdominal pain. Poor spirit, deep respiration, dehydration existed in all the patients. All the patients were improved and discharged after treatment with fluid replacement, redress acidosis and electrolyte disturbance, insulin supplement. Conclusion Clinical manifestations of diabetes mellitus with ketoacidosis as the first symptom are not specific. The inducement is always infection of which the symptoms are outstanding. It's easy to be ignored or make misdiagnosis. We should increase vigilance on DKA when the children have poor spirit or consciousness disorders, dehydration, deep respiration, vomiting and abdominal pain, unexplained fatigue or weight loss. Blood glucose, arterial blood gas analysis and urine examination should be checked and once the diagnosis is confirmed, the combined therapeutic measures are fluid replacement, insulin treatment,supplement of potassium actively and redress acidosis carefully.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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