Title: Clinical Comparative Study between Laparoscopy and Open Surgery in the Radical Treatment of Advanced Gastric Cancer
Abstract: Objective To evaluate the differences between laparoscopy and open surgery for treating advanced gastric cancer in peri-operative clinical and biochemical indexes,in order to investigate the superiority of laparoscopy in treating the disease.Methods The same including standards and double-blind randomized control study were carried out to compare the peri-operative clinical and biochemical indexes of 112 patients who underwent radical treatment for advanced gastric cancer from January to December 2010.Among them,59 patients were included in the laparoscopic group,and 53 in the traditional open operation group.Results Compared with the open surgery group,the incision length [(5.77±0.74) cm vs.(12.05±1.30) cm;t=-30.921,P=0.000],intraoperational blood loss [(107.20±27.23) mL vs.(168.87±96.76) mL;t=-4.483,P=0.000] and hospital stay time [(7.19±0.97) days vs.(8.32±1.16) days;t=-5.634,P=0.000] were significantly shorter or lower in the laparoscopic group.However,the operation time [(202.12±15.71) minutes vs.(196.32±16.73) minutes;t=1.891,P=0.061],number of lymph nodes removed(14.15±4.51 vs.15.25±5.17;t=0.736,P=0.471),and intestinal functioning time [(57.88±9.70) hours vs.(59.16±10.82) hours;t=-0.655,P=0.514] were not significantly different between the two groups.There was no significant difference between the two groups in the level of prealbumin and hemoglobin.Conclusion Compared with the traditional open operation,laparoscopic surgery for gastric cancer has obvious advantages including smaller incision,lower blood loss during the operation,and fast recovery,without aggravating patients′ traumatic response or increasing the incidence of operational complications.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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