Publication Information

{'id': 'https://openalex.org/W2380278248', 'doi': None, 'title': 'Investigate the effects of allicin on proliferation and apoptpsis of heptoma cell lines HepG2', 'display_name': 'Investigate the effects of allicin on proliferation and apoptpsis of heptoma cell lines HepG2', 'publication_year': 2008, 'publication_date': '2008-01-01', 'ids': {'openalex': 'https://openalex.org/W2380278248', 'mag': '2380278248'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-YXLY200806001.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764810485', 'display_name': 'Pharmaceutical and Clinical Research', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5070919649', 'display_name': 'Yaozuo Yuan', 'orcid': 'https://orcid.org/0000-0002-8602-776X'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Yuan Yao-zuo', 'raw_affiliation_strings': ['3Jiangsu Institute for Drug Control,Nanjing 210008,China'], 'affiliations': [{'raw_affiliation_string': '3Jiangsu Institute for Drug Control,Nanjing 210008,China', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5070919649'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 63}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11979', 'display_name': 'Garlic and Onion Studies', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11979', 'display_name': 'Garlic and Onion Studies', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2781005338', 'wikidata': 'https://www.wikidata.org/wiki/Q409641', 'display_name': 'Allicin', 'level': 2, 'score': 0.98305523}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.9123633}, {'id': 'https://openalex.org/C2776415932', 'wikidata': 'https://www.wikidata.org/wiki/Q48743', 'display_name': 'Western blot', 'level': 3, 'score': 0.7209465}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.7115411}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.70467997}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.59934336}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.51949084}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.46642786}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.45567355}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4548687}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.406209}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4042038}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.21684623}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.03888467}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-YXLY200806001.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764810485', 'display_name': 'Pharmaceutical and Clinical Research', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3031105918', 'https://openalex.org/W3029924262', 'https://openalex.org/W2997959760', 'https://openalex.org/W2889875685', 'https://openalex.org/W2789767397', 'https://openalex.org/W2411566250', 'https://openalex.org/W2393870434', 'https://openalex.org/W2393812990', 'https://openalex.org/W2384472374', 'https://openalex.org/W2375006766', 'https://openalex.org/W2373422015', 'https://openalex.org/W2370500222', 'https://openalex.org/W2369717833', 'https://openalex.org/W2367284899', 'https://openalex.org/W2358462102', 'https://openalex.org/W2353909922', 'https://openalex.org/W2353499761', 'https://openalex.org/W2347272947', 'https://openalex.org/W2054271757', 'https://openalex.org/W1991017315'], 'abstract_inverted_index': {'Objective:To': [0], 'investigate': [1, 26], 'the': [2, 19, 27, 30, 34, 41, 53, 65, 71, 112, 125, 136, 156], 'effects': [3], 'of': [4, 8, 29, 55, 67, 79, 95, 114, 150], 'allicin': [5, 62], 'on': [6], 'proliferation': [7, 28, 66, 105, 139], 'heptoma': [9], 'cell': [10, 32, 138, 142, 152], 'lines': [11], 'HepG2.Methods:': [12], 'Preparative': [13], 'HPLC': [14], 'was': [15, 23, 37, 49, 91, 122, 127], 'used': [16, 38, 50], 'to': [17, 25, 39, 51, 117, 129], 'purify': [18], 'allicin.Cell': [20], 'counting': [21], 'kit(CCK-8)': [22], 'exerted': [24], 'HepG2': [31, 72, 87, 137, 151], 'and': [33, 43, 69, 75, 81, 85, 93, 140, 144], 'flow': [35], 'cytometry': [36], 'detect': [40], 'apoptosis': [42, 56, 74, 80, 118, 130, 157], 'mortality': [44], 'rate,finally': [45], 'Western': [46], 'blot': [47, 108], 'method': [48], 'study': [52], 'expression': [54], 'protein.Results:': [57], 'Experimental': [58], 'results': [59, 109], 'showed': [60, 110], 'that': [61, 111], 'could': [63, 134, 146], 'inhibit': [64, 135], 'cells': [68, 73, 96, 104, 126], 'cause': [70, 141, 148], 'death,the': [76], 'highest': [77], 'ratios': [78], 'death': [82, 143], 'were': [83, 97, 106], '8.67%±3.2%': [84], '70.38%±1.8%,respectively.The': [86], 'cells′': [88], 'DNA': [89, 153], 'metabolism': [90, 154], 'disturbed': [92], 'most': [94], 'blocked': [98], 'in': [99, 103], 'G0/G1': [100], 'period': [101], 'resulting': [102], 'blocked.Western': [107], 'ratio': [113], 'protein': [115, 121, 158], 'corresponding': [116], 'bax/': [119], 'bcl-2': [120], 'increased': [123], 'indicating': [124], 'caused': [128], 'by': [131], 'allicin.Conclusion:': [132], 'Allicin': [133], 'apoptosis.Furthermore,allicin': [145], 'also': [147], 'disturbance': [149], 'disturbance,and': [155], 'increase': [159], 'its': [160], 'expression.': [161]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2380278248', 'counts_by_year': [], 'updated_date': '2024-12-14T20:05:31.903143', 'created_date': '2016-06-24'}