Title: Study on Optimization of the Hydrolysis Process of C_(21) Steroidal Glycoside of Bai Shou Wu by Hydrochloric Acid
Abstract: Objective To study the optimization of hydrolysis process of C21 steroidal glycoside of Bai Shou Wu by hydrochloric acid.Methods The effects of hydrochloric acid concentration,reaction temperature and reaction time had been investigated using orthogonal design with caudatin-3-O-β-D-cymaropyranosyl content as the index.Results The optimum hydrolysis condition was as follows: refluxing for 5 h with 50 mL of 0.5% dilute HCl solution at 60 ℃.Conclusion The content of active ingredients in general steroidal glycosides of Bai Shou Wu under the optimum hydrolysis condition is raised obviously and has a great part in improving anti-tumor activity.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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