Title: Comparative Study of Different Priming Scheme of Cardiopulmonary Bypass on Low Weight Infants with Congenital Heart Disease
Abstract: OBJECTIVE To evaluate the effects of different priming schemes of cardiopulmonary bypass (CPB) with ultrafiltration on organ edema in low weight infants with congenital heart disease (CHD) undergoing open heart surgery.METHODS 25 infants with CHD, weighed 7 kg or less (median weight 5.58 kg) underwent open heart surgery, were classified randomly into two groups according to the CPB priming scheme: routine group(n=12) and whole blood group(n=13). CUF or/and MUF were performed. RESULTS The priming volume of crystal solution, the ratio of crystal to colloid solution and the total diuretic dose post-CPB in whole blood group decreased markedly as compared with routine group (P0.05), however the urine volume post-CPB 24h in whole blood group increased significantly(P0.05). The high Hb concentrations was found during CPB in whole blood group as compared with routine group (P0.05), but there was no significant difference of Hb concentration between two groups at other time intervals. No significant difference between two groups was found in homologous blood transfusion volume, the net fluid input, and the duration of intubation (P0.05). No tissue edema and death occurred.CONCLUSION On the basis of the usage of ultrafiltration and blood a dynamical control of colloidality was an effective method to alleviate edema especially for infants under 7 kg with CHD undergoing open heart surgery. The whole blood priming inhances on discharging the body water post-CPB.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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