Title: The effect of rabeprazole combined with compound magnesium trisilicate and sodium bicarbonate tablets on peptic ulcer
Abstract:Objective To explore the effect of rabeprazole combined with compound magnesium trisilicate and sodium bicarbonate tablets on peptic ulcer.Methods Eighty-four peptic ulcer patients were randomly divid...Objective To explore the effect of rabeprazole combined with compound magnesium trisilicate and sodium bicarbonate tablets on peptic ulcer.Methods Eighty-four peptic ulcer patients were randomly divided into control group and observation group.The control group was given three joint programme:omeprazole + amoxicillin and clavu lanate potassium + metronidazole and the observation group was given four joint programme:rabeprazole + compound magnesium trisilicate and sodium bicarbonate tablets + amoxicillin and clavulanate potassium + metronidazole.The overall improvement of symptoms,ulcer healing and Hp eradicate rate at 4th week after treatment discontinuation and the adverse reactions during treatment of both groups were analyzed.Results The observation group's total efficiency of overall symptom improvement(95.24% vs 80.00%,P 0.05) and ulcer healing(97.62% vs 88.10%,P 0.01),cure rate(52.38% vs 30.95%,P 0.05) and Hp eradicate rate(80.95% vs 59.52%,P 0.01) were higher than control group.There was no significant difference on the adverse reactions(P 0.05).Conclusion Rabeprazole azole combined with compound belladonna bismuth magnesium is effective to treat the peptic ulcer treatment,improve the gen eral symptoms improve,ulcer healing Hp total effective rate and cure rate.Read More
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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