Title: Factors associated with bone loss in postmenopausal women with rheumatoid arthritis
Abstract:Objective:To evaluate disease related determinants of bone mineral density(BMD)in postmenopausal patients with rheumatoid arthritis(RA).Methods:Sixty-three postmenopausal RA patients demographic,clini...Objective:To evaluate disease related determinants of bone mineral density(BMD)in postmenopausal patients with rheumatoid arthritis(RA).Methods:Sixty-three postmenopausal RA patients demographic,clinical and BMD data were collected.Associations between demographic and clinical variables on the one hand and osteoporosis(OP)on the other were investigated in multiple regression analyses.Results:36.5% of patients had bone loss in at least one site.There were no relationships between bone loss and disease activity and also corticosteroid use.Logistic regressions showed that duration of menopause and X ray joint space narrowing(JSN) were the risk factors of bone loss(OR:1.298,95%CI:1.014-1.530,P=0.046 and OR:1.434,95%CI:1.057-1.946,P=0.020,respectively),and hormone replacement treatment(HRT) was the only protective factor of bone loss (OR:0.232,95%CI:0.057-0.952,P=0.032).Conclusion:OP is a common manifestation in postmenopausal RA patients.Long years of menopause and joint destruction are main risk factors of bone loss,and HRT can protect bone loss in the patients.Read More
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot