Title: Expression of MMP-9 in malignant breast tumor and its effect on the infiltration and metastasis of the fumor
Abstract: 【Objective】To study the expression of MMP-9 in benign and malignant tumor of breast,and the relationship between expression of MMP-9 and the status of lymph node in malignant tumor of breast.【Methods】Expression of MMP-9 in 35 samples of fresh breast cancer tissue from modified radical mastectomy and 30 samples of breast fibroadnoma was determined by immunohistochemistry(IHC)method.【Results】Expression of MMP-9 in breast cancer was higher than that in breast fibroadenoma(P0.001).Expression of MMP-9 in breast cancer with lymph node metastasis was higher than that in breast cancer without lymph node metastasis(P0.05).【Conclusions】MMP-9 may be a molecular marker for the infiltrating and metastatic characteristics of malignant tumor of breast with.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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