Title: Molecular Epidemiological Survey of Mycobacterium Tuberculosis in Henan Province
Abstract:Objective To explore molecular epidemiological distribution characteristics of mycobacterium tuberculosis in Henan province.Methods The M.tuberculosis strains were gained by multi-stratified grouping ...Objective To explore molecular epidemiological distribution characteristics of mycobacterium tuberculosis in Henan province.Methods The M.tuberculosis strains were gained by multi-stratified grouping random sampling method from the tuberculosis epidemiology survey in Henan and analyzed by IS6110-based RFLP DNA and DR-based Spoligotyping DNA fingerprinting. These fingerprinting patterns were clustered by Gel compare 4.1 software.Results 186 M.tuberculosis strains obtained from this survey can be conducted IS 6110 RFLP DNA fingerprinting analysis,among which 59.14%(110/186) were determined to be M.Tuberculosis strain by spoligotyping DNA fingerprinting analysis.Conclusion M.tuberculosis strains of Beijing Genotype are prevailing in Henan at present.Read More
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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