Title: Applications of Cystatin C in the Field of Kidney Disease
Abstract: Cystatin C is a protease inhibitor produced in a constant manner by nucleated cells.This molecule is freely filtrated by the glomerule and quite completely catabolized in the proximal tubules.Its plasmatic concentration might be endogenous maker of glomerular filtration rate(GFR).Many studies show that serum cystatin C is at least as good as serum creatinine to estimate GFR,and researchers induced some formulaes for estimating GFR based on cystatin C.In addition,urinary cystatin C has been found to be specific maker of renal tubular early dysfunction.This article reviews applications of cystatin C in the field of kidney disease.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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