Title: Effects of Qinggan Huoxue Decoction on Lipid peroxidation in Rat with Alcoholic Liver Disease
Abstract: Objective:To study effects of Qinggan Huoxue decoction (decoction of clearing liver and promoting blood circulation) on alcoholic liver disease(ALD). Methods:rat ALD models were induced by mixed liquids of ethanol, pyrazole and corn oil through consecutive gastric infusion in 14 weeks. The Qing gan Huo xue decoction treatment group were divided into low and digh dosage groups, while positive control group were treated with Xiao Chaihu decoction. The effects were studied as products of liver lipid peroxidition. Results:Experimental study showed the Qingan Huoxue decoction could depress the elevation level of ALT, AST, GGT, ALP and LDH, inhibit the levels of cytokines, decrease serum level of hyaluronic acid and laminin. Conclusion:The Qingan Huoxue decoction could prevent and cure ALD markedly, its mechanism might be adjusting immune function, anti-fubrosis, and inhibit inflections, promoting the metabolism of ethanol in liver.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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