Abstract: Eight of corresponding aryl acetic acids were synthesized from series substitutional acetophenone through Willgerodt-Kindler reset and hydrolysis reaction.The melting points of the products were in accord with those reported.Through the experiment on synthesis of 2,4-dihydroxyphenyl acetic acid,the influences of reaction time,the molar rate of raw materials and hydrolysis on the yield of the product were studied.The experimental results showed that the optimum conditions were as follows:reaction time 8 h,the molar ratio of 2,4-dihydroxyphenylethanone to morpholine 1∶3.75.The yield of the product was 75% under optimum condtions.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot