Publication Information

{'id': 'https://openalex.org/W2376096078', 'doi': None, 'title': 'Influence of Thalidomide on the level of plasma vascular endothelial growth factor and basic fibroblast growth factor in acute leukemia before and after treatment', 'display_name': 'Influence of Thalidomide on the level of plasma vascular endothelial growth factor and basic fibroblast growth factor in acute leukemia before and after treatment', 'publication_year': 2011, 'publication_date': '2011-01-01', 'ids': {'openalex': 'https://openalex.org/W2376096078', 'mag': '2376096078'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-YYCY201127027.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2765074935', 'display_name': 'China Medical Herald', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4322632788', 'host_organization_name': 'China University College of Medicine', 'host_organization_lineage': ['https://openalex.org/P4322632788'], 'host_organization_lineage_names': ['China University College of Medicine'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110374131', 'display_name': 'Miao Yudi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210160763', 'display_name': "Shaanxi Provincial People's Hospital", 'ror': 'https://ror.org/057ckzt47', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I17721919', 'https://openalex.org/I4210160763']}, {'id': 'https://openalex.org/I17721919', 'display_name': 'Shanxi Medical University', 'ror': 'https://ror.org/0265d1010', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I17721919']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Miao Yudi', 'raw_affiliation_strings': ["Department of Hematology,the People's Hospital of Shaanxi Province,Xi'an 710068,China"], 'affiliations': [{'raw_affiliation_string': "Department of Hematology,the People's Hospital of Shaanxi Province,Xi'an 710068,China", 'institution_ids': ['https://openalex.org/I4210160763', 'https://openalex.org/I17721919']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5110374131'], 'corresponding_institution_ids': ['https://openalex.org/I4210160763', 'https://openalex.org/I17721919'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 65}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10422', 'display_name': 'Angiogenesis and VEGF in Cancer', 'score': 0.9864, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10422', 'display_name': 'Angiogenesis and VEGF in Cancer', 'score': 0.9864, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11752', 'display_name': 'Cancer Treatment and Pharmacology', 'score': 0.9378, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10668', 'display_name': 'Endometrial and Cervical Cancer Treatments', 'score': 0.9369, 'subfield': {'id': 'https://openalex.org/subfields/2729', 'display_name': 'Obstetrics and Gynecology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/plasma-levels', 'display_name': 'Plasma levels', 'score': 0.44824088}], 'concepts': [{'id': 'https://openalex.org/C2777587049', 'wikidata': 'https://www.wikidata.org/wiki/Q20969945', 'display_name': 'Basic fibroblast growth factor', 'level': 4, 'score': 0.9015902}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.89478165}, {'id': 'https://openalex.org/C2777025900', 'wikidata': 'https://www.wikidata.org/wiki/Q29725', 'display_name': 'Vascular endothelial growth factor', 'level': 3, 'score': 0.78324676}, {'id': 'https://openalex.org/C2779609412', 'wikidata': 'https://www.wikidata.org/wiki/Q203174', 'display_name': 'Thalidomide', 'level': 3, 'score': 0.76011074}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6012691}, {'id': 'https://openalex.org/C167734588', 'wikidata': 'https://www.wikidata.org/wiki/Q4356503', 'display_name': 'VEGF receptors', 'level': 2, 'score': 0.5947641}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.54555386}, {'id': 'https://openalex.org/C2776863199', 'wikidata': 'https://www.wikidata.org/wiki/Q976388', 'display_name': 'Acute leukemia', 'level': 3, 'score': 0.49211282}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.48125812}, {'id': 'https://openalex.org/C2778461978', 'wikidata': 'https://www.wikidata.org/wiki/Q29496', 'display_name': 'Leukemia', 'level': 2, 'score': 0.45577407}, {'id': 'https://openalex.org/C3017575891', 'wikidata': 'https://www.wikidata.org/wiki/Q3918988', 'display_name': 'Plasma levels', 'level': 2, 'score': 0.44824088}, {'id': 'https://openalex.org/C2775960820', 'wikidata': 'https://www.wikidata.org/wiki/Q408378', 'display_name': 'Growth factor', 'level': 3, 'score': 0.35727578}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.32697874}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.06832716}, {'id': 'https://openalex.org/C2776364478', 'wikidata': 'https://www.wikidata.org/wiki/Q467635', 'display_name': 'Multiple myeloma', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-YYCY201127027.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2765074935', 'display_name': 'China Medical Herald', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4322632788', 'host_organization_name': 'China University College of Medicine', 'host_organization_lineage': ['https://openalex.org/P4322632788'], 'host_organization_lineage_names': ['China University College of Medicine'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3031082920', 'https://openalex.org/W2597718923', 'https://openalex.org/W2391826732', 'https://openalex.org/W2388547392', 'https://openalex.org/W2381901052', 'https://openalex.org/W2378368586', 'https://openalex.org/W2371064388', 'https://openalex.org/W2369160986', 'https://openalex.org/W2367829109', 'https://openalex.org/W2367694960', 'https://openalex.org/W2366718222', 'https://openalex.org/W2361402184', 'https://openalex.org/W2360095748', 'https://openalex.org/W2356481950', 'https://openalex.org/W2352119423', 'https://openalex.org/W2040882319', 'https://openalex.org/W160216830', 'https://openalex.org/W1599076667', 'https://openalex.org/W1537576787', 'https://openalex.org/W1511449329'], 'abstract_inverted_index': {'Objective:': [0], 'To': [1], 'observe': [2], 'the': [3, 7, 15, 59, 61, 79, 96, 159, 179, 194], 'clinical': [4], 'effect': [5, 207], 'and': [6, 23, 32, 47, 71, 85, 109, 123, 128, 132, 170, 199], 'influence': [8], 'of': [9, 17, 37, 81, 90, 106, 120, 125, 144, 147, 161, 197], 'Thalidomide': [10, 66, 173], 'combined': [11, 174], 'with': [12, 55, 100, 140, 156, 175, 184], 'chemotherapy': [13, 57, 176], 'on': [14, 208], 'level': [16, 119, 143, 160], 'plasma': [18, 121, 145, 162, 195], 'vascular': [19], 'endothelial': [20], 'growth': [21, 26], 'factor(VEGF)': [22], 'basic': [24], 'fibroblast': [25], 'factor(bFGF)': [27], 'in': [28, 58, 87, 182], 'acute': [29, 38, 185], 'leukemia': [30, 39], 'before': [31, 131], 'after': [33, 74, 133, 150], 'treatment.Methods:': [34], '36': [35], 'cases': [36, 89], 'patients': [40, 183], 'were': [41, 76, 93, 112, 137], 'randomly': [42], 'divided': [43], 'into': [44], 'experimental': [45, 62, 107, 126, 148, 168], 'group': [46, 52, 63, 108, 111, 127, 130, 149, 169], 'control': [48, 98, 110, 129, 157, 171], 'group,each': [49], '18': [50], 'cases.Each': [51], 'was': [53, 64, 116, 152], 'treated': [54], 'conventional': [56], 'standard-dose,meanwhile': [60], 'given': [65], '100': [67], 'mg/d': [68], 'additionally.Before': [69], 'treatment': [70, 134, 151], '8': [72], 'weeks': [73], 'treatment,plasma': [75], 'collected': [77], 'for': [78], 'detection': [80], 'VEGF,bFGF': [82], 'content.Plasma': [83], 'VEGF': [84, 122, 146, 198], 'bFGF': [86, 124, 163], '15': [88], 'healthy': [91, 141], 'people': [92], 'detected': [94], 'as': [95], 'standard': [97], 'value,compared': [99], 'Leukemia': [101], 'patients.Results:': [102], 'The': [103], 'effective': [104], 'rate': [105, 181], '88.9%(16/18),77.8%(14/18)': [113], 'respectively,the': [114], 'difference': [115, 136, 166], 'statistically': [117], 'significant(χ2=4.10,P0.05).The': [118], 'were[(389.78±249.94)ng/L,(211.74±36.72)ng/L],[(318.54±125.78)ng/L,(288.02±31.77)ng/L],[(2.43±0.27)μg/L,(2.09±0.17)μg/L],[(2.41±0.33)μg/L,(2.11±0.31)μg/L],the': [135], 'significant': [138], 'compared': [139, 155], 'group[(132.91±26.66)ng/L,(1.83±0.44)μg/L](P0.05);the': [142], 'significantly': [153], 'different': [154], 'group(t=2.79,P0.05),but': [158], 'shows': [164], 'no': [165], 'between': [167], 'group(t=1.28,P0.05).Conclusion:': [172], 'can': [177], 'improve': [178], 'remission': [180], 'leukemia,and': [186], 'its': [187, 200], 'mechanism': [188], 'may': [189], 'be': [190], 'conduced': [191], 'through': [192], 'inhibiting': [193], 'levels': [196], 'receptor': [201], 'expression': [202], 'to': [203], 'active': [204], 'anti-proliferative,then': [205], 'take': [206], 'anti-leukemia': [209], 'effection.': [210]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2376096078', 'counts_by_year': [], 'updated_date': '2024-12-08T15:51:00.519684', 'created_date': '2016-06-24'}