Title: To Explore Relationship Between Obstructive Sleep Apnea Syndrome and Hypertension
Abstract: Objective To explore the changes of arterial pressure in patients with snore during sleep and to increase the acknowledge for the relationship between obstructive sleep apnea syndrome(OSAS) and hypertension(HT).Methods 266 patients with snoring were monitored during overnight nocturnal sleep monitored with Autoset diagnosis-treatment system and measured arterial pressure before and after sleep.166 patients of them as OSAS group,the other 100 patients as controls.Data for each group such as Apnea Index,SaO 2 and arterial pressure were chosen for statistical analysis.Results The blood pressure in OSAS group before sleep was(128 94±19 32/87 46±12 30)mmHg,after sleep was(139 66±19 38/99 68±16 28)mmHg(P0 01).On the contrary,changes of arterial pressure in the controls had no significant difference before and after sleep[from(116 12±11 17/78 22±10 18)mmHg before sleep to(116 76±15 42/78 66±10 94)mmHg after sleep].The blood pressure in the OSAS group was increased remarkably than that in the controls(P0 01).The lowest SaO 2 in the OSAS group was decreased remarkably than that of the controls.[from (62 38±18 24)% to (89 46±7 66)%,P0 01],88 cases(53%) in the OSAS group were diagnosed as essential hypertension.But 52 cases blood pressure levels were decreased after effective nCPAP treatment for six months,27 cases of them recover to normal level.Conclusions The nocturnal hypoxemia may be considered as one of the causes of some OSAS patients with hypertension.Through nCPAP treatment,the hypertension may be recovered to normal value in the OSAS.The paper is to explore the mechanism of increasing blood pressure in the OSAS.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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