Title: Effect of PTFE covered stent with different diameters in TIPSS surgery of portal hypertension
Abstract: Objective To analyze effect of the different diameters(10 mm and 8 mm) PTFE covered stent in transjugular intrahepatic portosystemic stent shunt(TIPSS) surgery.Methods The clinical data of 46 patients who were diagnosed as portal hypertension and underwent TIPSS surgery was collected,including 20 patients treated with conventional 10 mm PTFE covered stent(10 mm group) and 26 patients with smaller diameter of 8 mm poly tetra fluoro ethylene(PTFE) covered stent(8 mm group).Portal vein pressure of the 46 patients was measured one week after surgery,as well as the initial opening ratio of shunt vein.The narrow ratio of shunt vein at different postoperative time points(3 months,6 months,9 months and 12 months) as well as the incidence of hepatic encephalopathy were detected.Results TIPSS surgery were successful and vital signs were stable intraoperative in 46 patients(100%),with no serious complications occurred.The ultrasound results of two groups showed initial opening ratio of shunt vein were both100%.The portal pressure of the two groups was(22.4±3.5) cmH2O,(23.2±3.7) cmH2O,respectively,significantly lower than the preoperative level.The fasting blood ammonia was(41.3±11.39) μg/L,(42.4±11.78) μg/L,respectively,slightly increased than preoperative level,with no significant difference between the two groups.The recurrence rate of gastrointestinal bleeding in the two groups was 10%,7.69% 9 months after surgery,and 15%,11.5% 12 months after surgery,respectively.Paired t-test statistics showed that the relapse rate of gastrointestinal bleeding and forward stenosis or occlusion of shunt vein in 8 mm group were significantly lower than those in 10 mm group(t=23.16,P0.01;t=14.21,P0.01).Conclusion The application of a smaller diameter PTFE covered stent(8 mm in diameter) of TIPSS would reach enough shunt effect and lower occurrence of complications such as stenosis or occlusion of shunt vein or stenosis in the long-term,withbetter prognosis.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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