Title: STUDIES ON QUERCETIN INDUCTION OF NB_4 CELL INHIBITION AND APOPTOSIS
Abstract: Objective:To study the role of quercetin which inhibit the proliferation of leukemia NB 4 cell line.Methods:The effect of quercetin on induction of NB 4 cell line apoptosis was studied by the cell number count,cell morphology,and DNA gel electrophoresis.Rusults:There was no significant difference in cell growth between the concentration of 10μM and control.The higher concentration results in mass death.We verify the results that the quercetin with concentration of (30~90)μmol/L can successfully inhibit the proliferation of NB 4 and the cell still showed apoptosis features.Conclusion:The quercetin with concentration of 30 μmol/L~90 μmol/L could successfully inhibit the proliferation of NB 4 cell lines in a dose ,time dependent manner and inducing apoptosis.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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