Title: Clinical study of renal transplantation in polycystic kidney patients
Abstract: Objective To investigate the characteristics,surgical techniques and therapeutic effects of renal transplantation of polycystic kidney patients.Methods A retrospective study of 25 renal allograft transplantation patients with polycystic kidney was carried out in our center.The size of polycystic kidney,hematuria and the graft function were observed before and after operation.Another 25 kidney transplantation patients with chronic glomerulonephritis served as controls.Results In the 25 polycystic kidney patients,1-year and 3-year patient/graft kidney survival rates were 96.0%/92.0% and 90.0%/90.0%,respectively.Acute rejection incidence was 28.0%(7 cases),2 cases(8.0%) lost graft function and 1 case((4.0)%) died.In the 23 patients,the original kidneys shrank after operation,with the left kidneys' length,width,height being(20.72±4.40)cm,(14.11±2.45)cm,(9.01±1.05)cm before operation and((14.70±)2.00)cm,(10.30±1.49)cm,(6.87±0.94)cm after operation,and the right kidneys' length,width,height being(20.11±2.64)cm,(15.10±2.14)cm,(9.18±0.96)cm before operation and((15.00±)(1.84))cm,(10.45±1.28)cm,(6.80±1.15)cm after operation,respectively(P0.05).The kidney functions were good,and the hematuria gradually disappeared.The blood pressure altered from preoperative(134.20±3.12)/(95.23±2.49)mm Hg(1 mm Hg=0.133 kPa) to postoperative(128.58±2.59)/(92.34±3.40)mm Hg(P0.05).In the controls,1-year and 3-year patient/graft kidney survival rates were 100.0%/100.0% and 96.0%/96.0%,respectively;and acute rejection incidence was 24.0%(6 cases),1 case(4%) lost graft function and 1 case(4%) died.Compared with polycystic kidney patients,these differences were not significant(all P0.05).Conclusions In the polycystic kidney patients undergoing kidney transplantation without the original kidneys removed,the therapeutic effects are good.Careful monitoring of hematuria,infection and graft kidney function is needed after transplantation.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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