Title: A Case of Multi-location Bowenoid Papulosis
Abstract: A rare case of multi-locaion bowenoid papulosis was reported.Methods The patient's clinical features and histopathological changes were analyzed,possible etiological factors were examined.Results Rapid plasma regain test (RPR) and treponema pallidum particle agglutination test (TPPA) are negative,human papilloma virus(HPV) type 16,18,31 and 33 DNA are undetected by in situ hybridization with digoxin labeled probes.Histologically,epidermis showed parakeratosis,acanthosis,pseudoepitheliomatous hyperplasia;spinous cell were disorder and various in size,Mitoses and dyskeratosis cells were present.The upper dermis had a mild lymphocytic infiltrate.In penis lesion,the disorder and verious keratocyte were more distinct,whereas in perianal lesion,vacuoler cells and dyskeratosis cells were abundantly present.Conclusion The case is unusual in its histopathological changes which had characteristic of condyloma acuminatum and may caused by other types of HPV except type 16,18,21,33.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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