Title: Investigation on reference intervals of kidney function tests among healthy children and adolescents based on dry chemical system in Shenzhen
Abstract: Objective To establish the reference intervals of urea, creatinine(Cr), uric acid(UA) on dry chemical system among healthy children and adolescents in Shenzhen. Methods A total of 1 401 blood samples from 760 male and 641 female healthy children and adolescents aged from 3 months to 18 years were collected. Kidney function tests in venous blood were detected by the VITROS 350 system, and data were analyzed by statistical methods. Results 1 The urea, Cr of 7~12 years old boys and urea, Cr, UA of 13~18 years old boys were significantly higher than those in girls(P0.05). The remaining items showed no significant differences between boys and girls(P0.05). 2 The reference intervals of 3 items were increased with age, showing significant differences in different age groups(P0.05). However,urea showed no significant difference between 4~6 years group and 7~12 years group, as well as between 7~12 years group and 13~18 years group. 3 The reference intervals of serum urea were 1.3~6.1 mmol/L for 3 months to 3 years group, 2.1~7.1 mmol/L for 3~18 years group. The reference intervals of Cr were 14.6~56.5 μ mol/L for 3 months to 3years group, 27.2~52.5 μmol/L for 4~6 years group, 27.5~60.1 μmol/L for 7~12 years group, 30.5~103.5 μmol/L for13~18 years group(male), and 29.2~88.6 μ mol/L for 13~18 years group(female). The reference intervals of UA were144.6~378.5 μmol/L for 3 months to 6 years group, 165.5~429.9 μmol/L for 7~12 years group, 185.9~465.7 μmol/L for13~18 years group(male), and 159.9~429.1 μmol/L for 13~18 years group(female). Conclusion The reference intervals of urea, Cr, UA were established on dry chemical system among healthy children and adolescents in Shenzhen.
Publication Year: 2016
Publication Date: 2016-01-01
Language: en
Type: article
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