Title: Clinical Efficacy of Glucomannan in Type 2 Diabetic
Abstract: Objective To investigate the effects of Glucomannan,glycemia control, and cardiovascular risk factors and to observe the safety and compliance of Glucomannan in type 2 diabetic patients.Methods They were randomized to receive G1ucomannan 5g tid(n=124)for 12 weeks and the effects of Glucomannan on reducing body weight,ameliorating blood glucose and lipids were evaluated.Results After 12 weeks,fasting plasma glucose of glucomannan-treated patients(-1.26±1.71)mmol/L(P0.001)、postprandial glucose(-2.15±2.18)mmol/L(P0.001)、HbAlc(-0.97±1.14)%(P0.001)、total cholesterol(-0.31±0.76) mmol/L(P0.001)、low-density 1ipoprotein cholesterol(-0.32±0.85)mmol/L(P0.01).Both groups had Similar adverseevent profiles,except for mostly mildand transient gastrointestinal events in glucomannan-treated patients.There were no serious adverse events in both groups.Conclusion Glucomannan may improve glycemia and high triglyceride control in Type 2 diabetics.Glucomannan may delay the absorption of carbohydrates.It could be concluded that glucomannan was very useful in both prevention and treatment of glycemia.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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