Title: The clinical effect of Rituximab combined with CHOP scheme in the treatment of elderly patients with non Hodgkin's lymphoma
Abstract:Objective To evaluate the clinical effect of Rituximab combined with CHOP scheme in the treatment of elderly patients with non Hodgkin's lymphoma( NHL). Methods Methods: 76 cases of elderly patients w...Objective To evaluate the clinical effect of Rituximab combined with CHOP scheme in the treatment of elderly patients with non Hodgkin's lymphoma( NHL). Methods Methods: 76 cases of elderly patients with NHL from October 2010 to October 2013 were randomly divided into two groups: 36 cases of CHOP group,40 cases of Rituximab combined with CHOP scheme group. The clinical curative effect of two groups were compared after 6 courses of treatment and the adverse reaction was recorded. Results The complete remission rate of CHOP group was 25%,and the total effective rate was 55. 56%; while the complete remission rate in Rituximab combined with CHOP scheme group was 45. 00%,and the total effective rate was 77. 50%,the total effective rate between two groups had statistically significant difference( χ2= 4. 133,P = 0. 042). The treatment adverse reaction rate between two groups had no significant difference( P0. 05). There were no statistical differences of IgA,IgG,IgM levels between the two groups before treatment( P0. 05),and they were higher than those before treatment( P0. 05),but there were no significant differences between the two groups after treatment( P0. 05). Conclusions The clinical effect of Rituximab combined with CHOP scheme in the treatment of elderlypatients with NHL is good and adverse reactions do not increase.Read More
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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