Title: Improved Preparation of Monomethyl Fumarate
Abstract: Monomethyl fumarate was synthesized with maleic anhydride and methanol as raw materials, phophoric acid and aluminium trichloride as catalysts, and toluene as solvent. The factors affecting the yield were investigated. The optimum conditions were as follows∶maleic anhydride∶methanol∶phosphoric acid∶aluminium trichloride, 0.2 mol∶0.2 mol∶4 mL∶2 g; temperature of esterification 60°C; esterification reaction time 0.5 h; temperature of isomerization, 80°C; isomerization reaction time 2 h. The yield was over 90%.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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