Title: Chromosomal analysis in the cases with the history of abnormal pregnancy.
Abstract: Objective: To investigate the relationship between abnormal pregnancy and cytogenetics. Methods: The peripheral blood in 229 couples with abnormal pregnancy were collected. The chromosomal karyotypes of peripheral lymphocytes in 229 couples with abnormal pregnancy were analyzed using G-banding after lymphocytes were treated with trypsin. Results: There were 34 abnormal karyotypes in 229 couples with abnormal pregnancy. The rate of abnormal karyotypes was 7.42%. Among the 34 cases of abnormal karyotypes, 6 cases of balanced translocation were discovered, it was 1.31% in all cases(17.65% in abnormal karyotypes); 1 case of robertsonian translocation was discovered, it was 0.22% in all cases(2.94% in abnormal karyotypes); 1 case of complex translocation was discovered, it was 0.22% in all cases(2.94% in abnormal karyotypes); 8 cases of pericentric inversion were discovered, it was 1.75% in all cases(23.53% in abnormal karyotypes); 18 cases of other abnormal karyotypes were discovered, it was 3.93% in all cases(52.94% in all abnormal karyotypes). Conclusion: The abnormality of chromosome is one of reasons of abnormal pregnancy.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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