Title: Exosomes in the Immune Response and Tolerance
Abstract: Exosomes, secreted by many live cells, are small non-cell vesicles with nanoparticle-grade size. In addition to the original function of discarding the uselessful membrane molecules, exosomes are involved in a range of immunoregulatory functions. Dendritic cell-derived exosomes and tumor-derived exosomes are the best characterized vesicles with potent anti- tumor effect by efficiently inducing immune response. Down-regulation of immune response or induction of immune tolerance is another interesting function of exosomes. Further functional studies of the exosomes will shed light on the application of exosomes.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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Cited By Count: 3
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