Title: Application of "Double C" program in blood glucose control of patients with refractory diabetes mellitus
Abstract: Objective To investigate the therapeutic effect of double C program which be consisted of continuous glucose monitoring system and continuous subcutaneous insulin infusion pump system in blood glucose control of patients with refractory diabetes mellitus.Methods 24 cases of patients with large blood glucose fluctuations,refractory and brittle diabetes mellitus were taken a 24 h continuous glucose monitoring firstly,then received continuous subcutaneous insulin infusion therapy by insulin pump for three days and evaluated the changes of blood glucose before and after treatment by continuous glucose monitoring system at the same time.Results Fasting blood glucose,postprandial blood glucose and night-time blood glucose(23:00)of patients after receiving insulin pump therapy three days were significantly lower compared with those before treatment(P0.05);Mean blood glucose(MBG)and mean amplitude of glycemic excursions(MAGE)of patients were significantly decreased compared with those before treatment(P0.05),which difference was statistically significant.Shared time percentage of blood glucose excursions(blood glucose11.1 mmol/L)were lower than before treatment(44%(19%-79%)vs17%(0-34%),P0.05),hypoglycemia event times were also significantly lower than before treatment(34.1 ± 11.4vs59.3±3.22,P0.05).Conclusion Double C program which combined continuous glucose monitoring system with continuous subcutaneous insulin infusion can control blood glucose more effective.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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