Title: Therapic Progress in Different Stage of Cervical Cancer
Abstract: Objective Treatment of invasive cervical cancer is affected by the stage of the disease, which is based on clinical evaluation. Method Reviewing later articles related therapic strategy of cervical cancer. Result Microinvasive carcinoma of the cervix has limited metastatic potential and therefore is most likely curable by non-radical treatment. Both radical surgery and radical radiotherapy have been proven to be effective equally, but differ in associated complications. In common, stage Ib1 cervical cancer is treated by radical hysterectomy with pelvic lymphadenectomy. Comparing with the modality, Laparoscopically assisted radical vaginal hysterectomy has shown similar efficacy and recurrence rates. In small cervical cancer where preservation of fertility is desired,radical vaginal trachelectomy with laparoscopic pelvic lymphadenectomy may be an option. Neoadjuvant chemotherapy followed by radical surgery may improve a survival in patients with stage Ib cervical carcinoma. Concomitant chemo-radiation is becoming a new standard in treatment of advanced disease, because it has been clearly shown to improve disease-free, progression-free and overall survival. Conclutions Treatment decisions should be individualized and based on multiple factors including the stage of the disease, age, medical condition of the patient, tumor-related factors and treatment preferences, to yield the best cure with minimum complications.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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