Title: Impact of numbers of embryos and prime embryo transfer on pregnancy outcome
Abstract: Objective: To explore the impact of numbers of embryos and prime embryos transfer at different ages on pregnancy outcome. Methods: Four thousand one hundred and ninety fresh cycles from infertile patients who underwent in vitro fertilization-embryo transfer(IVF-ET) were retrospectively analyzed. The patients were divided into group 1(younger than 35 years), group 2(between 35 and 37 years) and group 3(38 years and older). The pregnancy outcomes were compared and analyzed among the three groups. Results: ⑴In group 1, no statistically significant difference was found in clinical pregnancy rate, and the multiple pregnancy rate and ectopic pregnancy rate in patients who received two prime embryo transfer were higher than those who received one. ⑵In group 2, no statistically significant difference was found in clinical pregnancy rate whether two or three embryos transferred, and obviously higher than those who received one embryo transfer. The multiple pregnancy rate and ectopic pregnancy rate in patients who received three prime embryo transfer were obviously higher. ⑶In group 3, the clinical pregnancy rate was significantly lower than group 1 and group 2, and the multiple pregnancy rate and ectopic pregnancy rate in patients who received three prime embryo transfer were higher than those received one or two. Conclusion: One prime embryo transfer is advised for patients younger than 35 years, and one or two prime embryo transfer for the patients between 35~37 years. For the patients aged 38 and older, they should carefully select three prime embryos to reduce the risk of multiple pregnancy and ectopic pregnancy.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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