Title: Clinical value of detection of serum procalcitonin and C reactive protein in infants with severe pneumonia
Abstract: Objective To investigate the clinical value of serum procalcitonin values combined with C reaction protein in early diagnosis and judgement of disease severity of infants with severe pneumonia. Methods 68 cases of infant with severe pneumonia received and treated in the pediatric intensive care unit(PICU) of the present hospital from January 2011 to December 2013 were selected. The ages of the children were 30d to 3 years old, which were set as the observation group and included 40 cases of bacterial pneumonia, 18 cases of viral pneumonia and 10 cases of mycoplasma pneumonia. 30 healthy infants in the hospital for examination were set as the control group in the same periods. In the observation group, levels of serum procalcitonin(PCT), C reactive protein(CRP), and peripheral white blood cell(WBC) were detected at the first and third day after in PICU of the hospital, which were compared with that of the control group. Results The levels of PCT, CRP and WBC in observation group were all significantly higher than those in the control group(P 0.05). In the examination of serum procalcitonin, the positive rate of children with bacterial pneumonia was 90.00%, and the level of serum was significantly higher than that of the control group; In the detection of C reactive protein in children, the positive rate of children with bacterial pneumonia was 95.00%, and the positive rate of children with mycoplasma pneumonia was 90.00%. Conclusion Early in infants with severe pneumonia, serum procalcitonin and C reactive protein detection positive rate is higher, the help for the early diagnosis and prognosis of infants with severe pneumonia severity, and provide reliable basis for clinical rational use of antibiotics in time.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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