Title: Clinical analysis of 128 thrombocytopenia in pregnancy
Abstract:Objective:To explore the causes,manngement and outcome of pregnant women with thrombocytopenia.Methods:128 cases with thrombocytopenia were reviewed.Results:Thrombocytopenia was mainly caused by prena...Objective:To explore the causes,manngement and outcome of pregnant women with thrombocytopenia.Methods:128 cases with thrombocytopenia were reviewed.Results:Thrombocytopenia was mainly caused by prenacy-associated thrombocytopenia(PAT) in 91(71.09%) cases,idiopathic thrombocytopenia(ITP) in 11 cases(8.59%),hepatic disease in pregnancy in 10(7.81%) cases,pregnancy induced hypertension 14(10.94%) cases,Rhesus isoimmunization and viral infection each 1(0.78%) case.Thrombocytopenia was identified initially at 20~(+6) weeks of gestation,34(26.56%) cases were found before 28 weeks,94(73.44%)cases were found after 28 weeks.Prednisone was considered if the platelet count was less than 50×10~9/L.Platelet transfusion was given to those with platelet count less than 50×10~9/L before and after delivery.If the platelet count was less than 50×10~9/L esarean delivery might be performed.The occurrence of postpartum hemorrhage was 2.34%.Most cases of PAT recovered spontaneously within 1 week after delivery.Conclusion:Pregnancy thrombocytopenia usually becomes evident in the third trimester.PAT is the most common type of thrombocytopenia during pregnancy.Degree of thrombocytopenia with complication was more severe(platelet count usually less than 70×10~9/L).Half of ITP are symptomatic.Glucocorticoid is effective treatment for severe thrombocytopenia.Platelet transfusion may be considered when platelet count is still less than 50×10~9/L before opreation.Mother with ITP may affect infant.Read More
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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