Title: Impact of Complicated Hypertension in Type 2 Diabetes Mellitus on Autonomic and Peripheral Neuropathy
Abstract: Objective To investigate the impact of concurrent hypertension in patients with type 2 diabetes on autonomic and peripheral nerve lesions.Methods A total of 156 patients with type 2 diabetes mellitus were recruited.They were divided as hypertension group(n=76) and non-hypertension group(n=80) according to the hypertension diagnostic criteria,At the same period,60 healthy persons in healthy medical examination were enrolled as control group.The general data of all the subjects were collected,and their autonomic and peripheral nerve functions were tested.Results(1) The heart rate variability(HRV) parameters of the three groups showed statistically significant difference(P0.05).The HRV parameters were significantly lower in the hypertension and non-hypertension groups than in the control group(P0.05);and the HRV parameters were significantly lower in the hypertension group than in the non-hypertension group(P0.05).(2) The vibration perception threshold(VPT) parameters of the three groups showed statistically significant difference(P0.05).The VPT parameters were significantly higher in the hypertension and non-hypertension groups than in the control group(P0.05);however the VPT parameters between the hypertension group and the non-hypertension group showed no significantly difference(P0.05).Conclusion The hypertension complication in type 2 diabetes mellitus may have a certain influence on the autonomic nerve function,but have little effect on peripheral nerve function.So the type 2 diabetes patients complicated by hypertension need to be given autonomic nerve function test and active control of blood sugar and blood pressure as early as possible.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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