Title: Effects of Interferon Gamma (IFN-γ) and An.Fa.Te Treatment on Fibrosis in Chronic Hepatitis B Patients
Abstract: Objective To evaluate the efficacy of interferon gamma (IFN-γ) and An.Fa.Te in the treatment of chronic hepatitis B (CHB). Method Thirty-five CHB patients with liver fibrosis of greater than S2 were divided randomly into two groups. Twenty-two patients were treated with IFN-γ and An.Fa.Te for 36 weeks and patients in the control group were treated with liver-care medicine. Liver biopsy was performed before and after therapy. Biopsies were diagnosed according to the pathological grading and stage. Result The grading and the stage of liver fibrosis were significantly lower in patients after IFN-γ and An.Fa.Te treatment (P0.05). The grading was also lower than patients in the control group(P0.05). Conclusion Combination of IFN-?酌 and An.Fa.Te may be used to reduce fibrosis in the patients with CHB.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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