Title: The impact of Edaravone on serum matrix metalloproteinase 9 and prognosis of cerebral infarction patients
Abstract: Objective To investigate the impact of Edaravone on serum matrix metalloproteinase 9(MMP-9) and prognosis of patients with cerebral infarction.Methods 80 cases with cerebral infarction selected in the research were randomly divided into observation group and control group according to the random number table,40 cases in each group.The control group were treated with conventional therapy,while the observation group were given edaravone on the basis of conventional therapy.The efficacy and the serum MMP-9 and prognosis were compared before and after treatment between the two groups.Results There were no significant differences between the two groups(u=1.263,P=0.206).After treatment,the content of serum MMP-9 reduced significantly,and especially the observation group decreased more significantly.The differences were significant(P0.05).Conclusion The efficacy of Edaravone on the treatment of cerebral infarction patients was exact.It can significantly improve the prognosis of patients,probably related to the regulation of MMP-9.It is worthy of promotion and application in clinic.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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