Title: Research progress on DNA double-strand break repair in Deinococcus radiodurans
Abstract: Deinococcus radiodurans is a popular model organism to study DNA double-strand break(DSB) repair due to its high resistance to DNA damage agents such as radiation. D. radiodurans can efficiently repair more than 100 DSBs per genome copy within dozens of hours. It has been shown that homologous recombination, non-homologous end joining and single strand annealing are three major pathways involved in the DSB repair of D. radiodurans. Additionally, a series of novel proteins were also identified, which play important roles in DSB repair. In this article, we summarized the recent progresses on DSB repair in D. radiodurans by different DNA repair pathways.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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