Title: Optimization of the alcohol extracting technology of Aucklandia lappa for the preparation of Jiangxiang patch by orthogonal test
Abstract: Objective To optimize alcohol extract technology from root of Aucklandia lappa for the preparation of Jiangxiang patch.Methods An orthogonal test was used to evaluate the influence factors including the concentration of alcohol,the ratio of alcohol to drug material,extraction times and numbers,and the contents of costunolide and dehydrocostuslactone were used as an index.Results The optimum process consists of dissolved in 6 times of 80% alcohol,extracting for 3 times at 1 hour each time.Conclusion The process may be the base of the preparation of percutaneously controlled-release drug delivery system by reducing the dose and improving the quality.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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