Title: Effect of Danhong injection on oxidative stress and inflammation reaction in patients with acute myocardial infarction undergoing percutaneous coronary intervention
Abstract: OBJECTIVE To investigate the effects of Danhong injection on oxidative stress and inflammation reaction in patients with acute myocardial infarction undergoing percutaneous coronary intervention(PCI).METHODS 180 patients with acute myocardial infarction undergoing PCI were randomly divided into Danhong treatment group(n=90)and control group(n= 90).Conventional western medicines were given for patients in both groups except Danhong injection was given at the dose of 30 ml per day for patients in Danhong treatment group.The serum levels of SOD,hs-CRP were analyzed before and after10 days treatment.RESULTS(1)The clinical therapeutic efficacy was significantly different in patients with Danhong treatment compared to control group(P0.05);(2)the serum level of SOD was significantly increased after 10days treatment in both Danhong and control groups though the increase was more obvious in Danhong treatment group.The serum level of hs-CRP in both groups was significantly decreased after 10 days treatment(P0.05).And this decrease was more significant in Danhong treatment group compared to control group.CONCLUSION Danhong injection can reduce the consumption of SOD,effectively remove free oxygen radicals,suppress oxidative stress,and alleviate the inflammation reaction,so as to stabilize artery atheromatous plaque and improve prognosis in AMI patients undergoing PCI.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot