Title: Clinical Efficacy of Heche Dazao Capsule Combined with Climen in Treatment of Premature Ovarian Failure
Abstract: Objective To observe the clinical efficacy of Heche Dazao Capsule combined with Climen in the treatment of premature ovarian failure.Methods Forty-one patients with premature ovarian failure were randomly divided into treatment group(n=21)and control group(n=20).Patients in the control group were given Climen by oral administration,while patients in the treatment group were given Heche Dazao Capsule combined with Climen.The treatment lasted for three cycles,with 21 days in each cycle.Before and after treatment,the clinical outcomes in the two groups were observed,and the levels of follicle stimulating hormone(FSH),luteinizing hormone(LH),and estradiol(E2)were determined.Results The overall response rate in the treatment group was significantly higher than that in the control group(85.70%vs 55.00%,P0.05).The serum FSH levels in both groups were significantly reduced after treatment(P0.05),while the E2 levels in both groups were significantly increased after treatment(P0.05).However,there were no significant changes in LH levels in both groups after treatment(P0.05).There were also no differences in FSH reduction and E2 increase after treatment between the two groups(P0.05).Conclusion Heche Dazao Capsule combined with Climen can improve clinical outcomes and regulate serum levels of sex hormone in the treatment of premature ovarian failure,which,however,still needs to be confirmed by data with a large sample size.
Publication Year: 2015
Publication Date: 2015-01-01
Language: en
Type: article
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Cited By Count: 1
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