Publication Information

{'id': 'https://openalex.org/W2365317169', 'doi': None, 'title': 'Expression of VEGF, HIF-1 alpha and EGF in hepatocellular carcinoma', 'display_name': 'Expression of VEGF, HIF-1 alpha and EGF in hepatocellular carcinoma', 'publication_year': 2004, 'publication_date': '2004-01-01', 'ids': {'openalex': 'https://openalex.org/W2365317169', 'mag': '2365317169'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHPZ200406016.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764824895', 'display_name': 'Zhonghua putong waike zazhi', 'issn_l': '1007-631X', 'issn': ['1007-631X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5013773205', 'display_name': 'Huang Geng', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Huang Geng', 'raw_affiliation_strings': ['wen, YANG Lian  yue, LU Wei  qun, YANG Jian  qing,LIU He  li'], 'affiliations': [{'raw_affiliation_string': 'wen, YANG Lian  yue, LU Wei  qun, YANG Jian  qing,LIU He  li', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5013773205'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 61}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10631', 'display_name': 'Metabolic Reprogramming in Cancer Biology', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10631', 'display_name': 'Metabolic Reprogramming in Cancer Biology', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10073', 'display_name': 'Hepatocellular Carcinoma', 'score': 0.958, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hepatocellular-carcinoma', 'display_name': 'Hepatocellular Carcinoma', 'score': 0.523025}, {'id': 'https://openalex.org/keywords/hypoxia', 'display_name': 'Hypoxia (environmental)', 'score': 0.50992143}, {'id': 'https://openalex.org/keywords/alpha', 'display_name': 'Alpha (finance)', 'score': 0.4279364}], 'concepts': [{'id': 'https://openalex.org/C2778019345', 'wikidata': 'https://www.wikidata.org/wiki/Q1148337', 'display_name': 'Hepatocellular carcinoma', 'level': 2, 'score': 0.8339766}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.7654944}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7425962}, {'id': 'https://openalex.org/C2777025900', 'wikidata': 'https://www.wikidata.org/wiki/Q29725', 'display_name': 'Vascular endothelial growth factor', 'level': 3, 'score': 0.70101374}, {'id': 'https://openalex.org/C2776362946', 'wikidata': 'https://www.wikidata.org/wiki/Q424374', 'display_name': 'Epidermal growth factor', 'level': 3, 'score': 0.68276954}, {'id': 'https://openalex.org/C167734588', 'wikidata': 'https://www.wikidata.org/wiki/Q4356503', 'display_name': 'VEGF receptors', 'level': 2, 'score': 0.59086794}, {'id': 'https://openalex.org/C7836513', 'wikidata': 'https://www.wikidata.org/wiki/Q1641506', 'display_name': 'Hypoxia (environmental)', 'level': 3, 'score': 0.50992143}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.49111745}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4477364}, {'id': 'https://openalex.org/C64943373', 'wikidata': 'https://www.wikidata.org/wiki/Q2651003', 'display_name': 'Alpha (finance)', 'level': 4, 'score': 0.4279364}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.38977653}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.36867803}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.18123859}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.08144623}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.055583626}, {'id': 'https://openalex.org/C49453240', 'wikidata': 'https://www.wikidata.org/wiki/Q1592163', 'display_name': 'Construct validity', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C540031477', 'wikidata': 'https://www.wikidata.org/wiki/Q629', 'display_name': 'Oxygen', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C2775944032', 'wikidata': 'https://www.wikidata.org/wiki/Q22907659', 'display_name': 'Patient satisfaction', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHPZ200406016.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764824895', 'display_name': 'Zhonghua putong waike zazhi', 'issn_l': '1007-631X', 'issn': ['1007-631X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/1', 'score': 0.48, 'display_name': 'No poverty'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W860395343', 'https://openalex.org/W3032353300', 'https://openalex.org/W2472531941', 'https://openalex.org/W2411253791', 'https://openalex.org/W2395466562', 'https://openalex.org/W2391888336', 'https://openalex.org/W2390255641', 'https://openalex.org/W2387358328', 'https://openalex.org/W2385374080', 'https://openalex.org/W2382176179', 'https://openalex.org/W2377907586', 'https://openalex.org/W2371563020', 'https://openalex.org/W2366179528', 'https://openalex.org/W2362846252', 'https://openalex.org/W2361664764', 'https://openalex.org/W2355989395', 'https://openalex.org/W2348003856', 'https://openalex.org/W2347594783', 'https://openalex.org/W2220401549', 'https://openalex.org/W2023476291'], 'abstract_inverted_index': {'Objective': [0], 'To': [1], 'investigate': [2], 'the': [3, 153, 157, 225], 'expressions': [4, 34, 212], 'of': [5, 35, 44, 64, 95, 152, 203, 213, 231], 'vascular': [6], 'endothelial': [7], 'growth': [8, 21], 'factor': [9, 14, 22], '(VEGF)': [10], ',': [11], 'hypoxia': [12], 'inducible': [13], '1': [15], 'alpha': [16], '(HIF': [17], '1α)': [18], 'and': [19, 28, 39, 46, 50, 68, 76, 85, 97, 135, 143, 174, 186, 188, 207, 217, 228], 'epidermal': [20], '(EGF)': [23], 'in': [24, 41, 70, 82, 100, 111, 129, 137, 145, 176, 181, 190, 209, 219], 'hepatocellular': [25], 'carcinoma': [26], '(HCC)': [27], 'their': [29], 'clinical': [30], 'significance.': [31], 'Methods': [32], 'The': [33, 93, 121, 150, 166, 211], 'VEGF,': [36, 65, 204, 214], 'HIF': [37, 66, 98, 205, 215], '1α': [38, 67, 99, 206, 216], 'EGF': [40, 69, 177, 182, 191, 208, 218], '36': [42], 'cases': [43], 'HCC': [45, 71, 101, 112, 132, 179, 220], 'corresponding': [47], 'paraneoplastic': [48, 83], 'tissues': [49, 53, 84, 88], 'normal': [51, 86], 'liver': [52, 87], '(6': [54], 'cases)': [55], 'were': [56, 106, 127, 160, 172], 'studied': [57], 'by': [58], 'immunohistochemistry': [59], 'assay.': [60], 'ResultsThe': [61], 'expression': [62, 94], 'rate': [63], 'tissue': [72], 'was': [73], '89%,': [74], '67%': [75], '75%': [77], 'respectively,': [78], 'higher': [79, 108], 'than': [80, 109], 'those': [81, 110], '(': [89, 117, 162, 195], 'P': [90, 118, 163, 196], '0': [91, 119, 144, 164, 189, 197], '05).': [92, 120, 165, 198], 'VEGF': [96, 130, 138, 146], 'with': [102, 224], 'microscopic': [103, 114], 'venous': [104, 115], 'invasion': [105, 116], 'significantly': [107], 'without': [113], '1,': [122, 167], '2': [123, 168], 'year': [124, 169], 'survival': [125, 154, 170], 'rates': [126, 155, 171], '100%': [128, 173], 'negative': [131, 178], 'group,': [133, 141], '87%': [134], '22%': [136], 'slight': [139, 183], 'positive': [140, 148, 184, 193], '54%': [142], 'strong': [147, 192], 'group.': [149], 'differences': [151], 'among': [156], 'three': [158], 'groups': [159], 'significant': [161], '60%': [175], 'group,70%': [180], 'group': [185, 194], '27%': [187], 'Conclusions': [199], 'There': [200], 'are': [201, 221], 'overexpression': [202], 'HCC.': [210, 232], 'closely': [222], 'correlated': [223], 'malignant': [226], 'behaviors': [227], 'poor': [229], 'prognosis': [230]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2365317169', 'counts_by_year': [], 'updated_date': '2024-09-18T23:25:52.653138', 'created_date': '2016-06-24'}