Title: Treatment of Unresectable Large Primary Hepatocellular Carcinoma by Multi-Electrode Radiofrequency Ablation Combined with Transcatheter Hepatic Arterial Chemoembolization
Abstract: Objective:To evaluate clinical efficacy of multi-electrode radiofrequency ablation(RFA) combined with transcatheter hepatic arterial chemoembolization(TACE) in treatment of unresectable large primary hepatocellular carcinoma.Methods:23 patients,who had 30 large HCC nodules,(5.3) to 12.0 cm in diameter with the mean size of(6.4 cm),were treated by RFA combine with TACE.Results:In 18 patients with elevated alpha-fetoprotein(AFP) level,the AFP level decreased in 15 patients after RFA and TACE.Repeated biopsies on 6 cases showed completely destruction.The 1-year survived rate was 73%(14/19).In the patients alive,three ones continued to survive for more than four years,one for more than six years.Conclusion:RFA combine with TACE is a safe and effective method in treatment of unresectable large primary hepatocellular carcinoma.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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