Title: Changing pattern of bacterial resistance in Gram negative bacilli
Abstract:Objective: To investigate the bacterial resistance of Gram negative bacilli isolated from eleven Shanghai hospitals. Methods: Antimicrobial susceptibility of clinical isolates were tested by Kirby Bau...Objective: To investigate the bacterial resistance of Gram negative bacilli isolated from eleven Shanghai hospitals. Methods: Antimicrobial susceptibility of clinical isolates were tested by Kirby Bauer method. ESBLs of these isolates were detected by method recommended by NCCLS 1999. Results: Of 13?934 Gram negative bacilli, 8?686(62.3%) were Enterobacteriaceae, 5?248(37.7%) were non fermentative bacilli. The most common species were E. coli , Klebsiella spp, P. aeruginosa , Acinetobacter spp and Enterobacter spp. etc. Among them, strains of non fermentative bacilli especially strains of S. maltophilia were increasing in recent years. The resistant rates of different species were slightly higher than those of last year. The antibacterial activity of antimicrobial agents tested against Enterobacteriaceae strains were IMP, MEMFEPCPZ SBT, PIP TAZ, AMKCAZCIP, while the activity against nonfermenters were IMP, MEMCPZ SBT, PIP TAZCAZ, CIPFEP,AMK. IMP is as active against Gram negative bacilli as MEM. Strains of Enterbacteriaceae were as susceptible to CPZ SBT as to PIP TAZ, the susceptibility of non fermentative Gram negative organisms to CPZ SBT was similar to that of PIP TAZ, however, the number of strains resistant to PIP TAZ were more than those resistant to CPZ SBT. Conclusion: Our data may have great significance in the empirical use of antimicrobial agents for the treatment of infections caused by Gram negative bacilli.Read More
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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Cited By Count: 2
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