Title: Effect of Metoprolol on Heart Rate Variability in Patients with Angina Pectoris in Coronary Heart Disease
Abstract: Objective To evaluate the effect of Metoprolol on heart rate variability(HRV) of patients with angina pectoris in coronary heart disease(CHD) by Holter electrocardiogram.Methods One hundred and twenty patients with angina pectoris in CHD and frequent arrhythmia were randomly divided into control group(n=62) and Metoprolol group(n=58).HRV in twenty four hours was measured by Holter electrocardiogram and evaluated before and after administration.Results HRV was significantly increased in both groups after treatment(P0.01).The difference of HRV between the two groups after treatment was significant(P0.01).Conclusion Metoprolol can significantly improve HRV of patients with angina pectoris in CHD.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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