Title: A control study of TACE using high-dosed and routine-dosed iodized oil as a treatment of large hepatocellular carcinoma
Abstract: Objective To investigate the side effects and curative effect in high-dosed lipiodol-transcatheter arterial chemoembolization as a treatment of large hepatocellular carcinoma. Methods 79 patients with unresectable hepatocell ular carcinoma were treated by TACE, and divided into 2 groups. In group A, 39 patients with the tumor sized 7-18cm in diameter, routine-dosed, 10-20ml lipio dol was given in TACE. 40 patients were enrolled in the high-dosed group B, who were given more than 20ml iodized oil in TACE. Results The First to third year survival rate of group A was 66.7%, 33.3 %, 0%respectively,while in group B it was 75%, 45%, 7.5%respectively. The effective rate was 71.7%in Group A an d 87.5%in Group B. There was a significant difference between both groups. Ther e was no significant difference of critical side effects and liver function dama ge between group A and B. Conclusion High-dosed lipiodol chemoembolization as a treatment of unresectable hepatocellular carcinoma is superior to the routine TACE, especially when the tumor is large and the liver function reserve is good.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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