Title: Detection of SRY Gene and the relationship with karyotype in 36 patient of sex abnormality
Abstract: Objective:To investigate the relationship between Karyotype and SRY gene in patients of sex abnormality with differentiation and development.Methods:SRY gene detection with polymerase chain reaction(PCR) and karyotype were detected in 36 patients of sex abnormality.Results:10 cases SRY +,2 cases SRY-in 12 Turner,s syndrome;5 cases SRY +,2 cases SRY-in pure female sex gland abnormality.3 cases 47,XXY,2 cases SRY +,1 cases SRY-;in 7 cases pure testis abnormality,5 cases SRY +,2 cases SRY-.2 females 46,XY,SRY +,1man 46,XX,SRY-.Conclusion:SRY gene play an important role in sex differentiation and development.Detecting SRY gene will provide differential diagnosis for patients of sex abnomole.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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