Title: Retrospective Study on Fertility-sparing Surgery in Uterine Sarcoma
Abstract: Objective To study the feasibility of application of fertility-sparing surgery in nulliparous patients with uterine sarcoma.Method Records of nulliparous patients younger than 35 years diagnosed as stage I uterine sarcoma admitted in the First Affiliated Hospital of Sun Yat-sen University treated with fertility-sparing surgery during Jan.2002 to Dec.2009 were reviewed.Results Six patients were enrolled in this study.Median age was 26 years(20~34 years).Two of 6 patients were confirmed by pathological examination as sarcomatous degeneration of leiomyoma.Leiomyosarcoma was limited in leiomyoma with tumor-free surgical margin in both cases.One patient had cesarean section at term pregnancy subsequently.Another one had total hysterectomy as she requested 28 months later and pathological examination found no malignant tissue.Four of 6 patients were confirmed by pathological examination as low-grade endometrial stromal sarcoma.In 3 of 4 cases,low-grade endometrial stromal sarcoma lesions were found on the uterus during subsequent surgery because of later image evidence of occurrence of uterine tumor.In the other case,total hysterectomy was performed as the patient requested 2 months later and pathological examination found no malignant tissue.Conclusion With strict follow-up,selected cases of uterine sarcoma might be managed with fertility-sparing surgery.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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