Title: The role of new contrast agent and contrast-enhanced gray-scale ultrasound in the diagnosis of liver neoplasms
Abstract: Objective To investigate the role of new contrast agent and real time gray scale contrast tuned imaging in the evaluation of the perfusion and echogenicity of liver neoplasms and to discuss the diagnostic value.Methods Thirty five patients with unconfirmed liver neoplasms were enrolled in the study.Nine of them were diagnosed clinically,while the other 26 cases with pathological evidence through surgery or needle biopsy.Contrast agent SonoVue,Technos DU6 and CnTI technology were used.The contrast agents were delivered intravenously or through bolus injection.Results Timing of all phases following contrast injection in normal and cirrhotic liver was observed.And then the perfusion processs of liver neoplasms was recorded.Among the 23 cases of typical hepatocellular carcinoma(HCC),21 cases(91%) presented with early artery enhancement and immediate wash out,while the other 2 cases of small(2 cm) hyper differentiated HCC washed out slowly after early artery enhancement.The enhancement pattern of 5 liver metastasis cases was diverse,including peripheral or various degree enhancement in the arterial or portal phase with slow or fast wash out.The 3 cases of haemoangioma were enhanced centripetally in portal phase and washed out slowly after several minutes without arterial enhancement.For HCC,the lesions could reach the peak of enhancement much faster by bolus injection other than intravenously injection.Thirty one patients underwent conventional ultrasound,contrast ultrasound and contrast CT,and the number of detected lesions was 76,99,75,respectively.Contrast ultrasound found more new lesions mostly 3~10 mm in diameter in 11 patients,and enlarged lesions in 5 patients.Conclusions New contrast specific ultrasound technique is significantly superior to conventional ultrasound in liver neoplasm diagnosis,superior to contrast CT in detecting more lesions especially minute ones,thus greatly improves the value of ultrasound in liver neoplasm diagnosis.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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Cited By Count: 1
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