Title: Determination of Radix Salviae Miltiorrhizae and compound Danshen tablets by substitute reference substance
Abstract: Objective:To established an HPLC method for determination of Radix Salviae Mihiorrhizae and compound Danshen tablets by substitute reference substance. Method:To measure the correction factor of Salvianolic acid B under different condition;Assay of Radix Salviae Mihiorrhizae and compound Danshen tablets was determined by substitute reference substance and the correct factor. Results: The linear response ranges (n=7) of salvianolic acid B and methylparaben were 0.09-2.71μg(r=1.0000) and 0.015-0.45μg(r=1.0000),respectively. The correction factor (f) was 5.2884. The average recovery was 100.5% (n=9). Conclusion: For the first time, the substitute reference substance is adopted in HPLC determination of Radix Salviae Miltiorrhizac and compound Danshen tablets. The assay demonstrates that the method is feasible and applied for quality control of Radix Salviae Miltiorrhizae and compound Danshen tablets.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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Cited By Count: 2
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