Title: Diagnostic value of serum cystatin C for nonage renal function injury caused by hypertension and diabetes mellitus
Abstract: Objective To study the clinical value of serum Cys-C levels in the patients with nonage renal function injury caused by hypertension and diabetes mellitus(DM).Methods Serum specimen of 22 patients with hypertension,28 patients with DM and 44 nephrotic patients were collected;Cr and BUN levels in serum were detected with enzymic method,cystatin in serum with grains strengthen immunotur-bidimetry (ITM), β2-mg with RIA. Results The abnormal rate for serum cystatin and β2-mg was significantly higher than that of Cr and BUN,the serum cystatin levels in hypertension and diabetic patient were significantly higher than normal control, all the detection item of degenerative nephrosis group was all higher than hypertension, diabetic patient and normal control group.Conclusion For the diagnosis of renal damage in early stage,the sensitivity of serum Cys-C is lower than β2-mg, but its specificity is better; in combined comparison serum Cys-C levels could be one of the additive diagnostic items.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot