Title: The efficacy of etanercept in treatment of ankylosing spondylitis and effect of etanercept on S-CTX level
Abstract: Objective To obersve the efficacy of etanercept in treatment of ankylosing spondylitis and the effect of etanercept on S-CTX level. Methods 206 patients with ankylosing spondylitis were randomly divided into observation group and control group,each of 103 cases. The control group was received non steroidal anti-inflammatory drug treatment,observation group which based on the control group,used the etanercept for treatment. The two groups were treated for 3 months,and then compared the clinical efficacy and S-CTX level changes between the two groups. Results The total effective rate of observation group was higher than that of the control group; Before treatment,the differece of S-CTX level between the two groups was not statistically significant( P 0. 05). After treatment,the S-CTX level of the two groups decreased,and the decrease of observation group was greater than the control group,the differences were statistically significant( P 0. 05). Conclusion Etanercept in treatment of ankylosing spondylitis has good treatment effect,and can decrease S-CTX level significantly,which is worth the clinical promotion.
Publication Year: 2015
Publication Date: 2015-01-01
Language: en
Type: article
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