Publication Information

{'id': 'https://openalex.org/W2360978323', 'doi': None, 'title': '[Erythropoietin administration protects retina against light-induced retinal degeneration].', 'display_name': '[Erythropoietin administration protects retina against light-induced retinal degeneration].', 'publication_year': 2005, 'publication_date': '2005-05-01', 'ids': {'openalex': 'https://openalex.org/W2360978323', 'mag': '2360978323', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15938809'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15938809', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101635645', 'display_name': 'Hongyun Wang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I108688024', 'display_name': 'Qingdao University', 'ror': 'https://ror.org/021cj6z65', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I108688024']}, {'id': 'https://openalex.org/I4210116869', 'display_name': 'Affiliated Hospital of Qingdao University', 'ror': 'https://ror.org/026e9yy16', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210116869']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hong-yun Wang', 'raw_affiliation_strings': ['Department of Ophthalmology, the Affiliated Hospital, the Medical School of Qingdao University, Qingdao 266003, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, the Affiliated Hospital, the Medical School of Qingdao University, Qingdao 266003, China.', 'institution_ids': ['https://openalex.org/I108688024', 'https://openalex.org/I4210116869']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028303703', 'display_name': 'Ying-jun Niu', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ying-jun Niu', 'raw_affiliation_strings': ['266003,青岛大学医学院附属医院眼科'], 'affiliations': [{'raw_affiliation_string': '266003,青岛大学医学院附属医院眼科', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103205372', 'display_name': 'Peisong Wang', 'orcid': 'https://orcid.org/0000-0003-3222-938X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Pei-song Wang', 'raw_affiliation_strings': ['266003,青岛大学医学院附属医院眼科'], 'affiliations': [{'raw_affiliation_string': '266003,青岛大学医学院附属医院眼科', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083616897', 'display_name': 'Zhanyu Zhou', 'orcid': 'https://orcid.org/0000-0001-5652-2367'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Zhan-yu Zhou', 'raw_affiliation_strings': ['266003,青岛大学医学院附属医院眼科'], 'affiliations': [{'raw_affiliation_string': '266003,青岛大学医学院附属医院眼科', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046346795', 'display_name': 'Fu-ling Liu', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Fu-ling Liu', 'raw_affiliation_strings': ['266003,青岛大学医学院附属医院眼科'], 'affiliations': [{'raw_affiliation_string': '266003,青岛大学医学院附属医院眼科', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087648305', 'display_name': 'Wen‐Yi Yang', 'orcid': 'https://orcid.org/0000-0003-1279-0866'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wen-yi Yang', 'raw_affiliation_strings': ['266003,青岛大学医学院附属医院眼科'], 'affiliations': [{'raw_affiliation_string': '266003,青岛大学医学院附属医院眼科', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5065075495', 'display_name': 'Yuehong Zhang', 'orcid': 'https://orcid.org/0000-0002-1990-9439'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yue-hong Zhang', 'raw_affiliation_strings': ['266003,青岛大学医学院附属医院眼科'], 'affiliations': [{'raw_affiliation_string': '266003,青岛大学医学院附属医院眼科', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.509195, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 61, 'max': 68}, 'biblio': {'volume': '41', 'issue': '5', 'first_page': '434', 'last_page': '8'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10170', 'display_name': 'Retinal Diseases and Treatments', 'score': 0.9316, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10170', 'display_name': 'Retinal Diseases and Treatments', 'score': 0.9316, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11438', 'display_name': 'Retinal Imaging and Analysis', 'score': 0.9218, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/outer-nuclear-layer', 'display_name': 'Outer nuclear layer', 'score': 0.91990495}, {'id': 'https://openalex.org/keywords/inner-nuclear-layer', 'display_name': 'Inner nuclear layer', 'score': 0.7011053}], 'concepts': [{'id': 'https://openalex.org/C2778231335', 'wikidata': 'https://www.wikidata.org/wiki/Q4113701', 'display_name': 'Outer nuclear layer', 'level': 3, 'score': 0.91990495}, {'id': 'https://openalex.org/C2777093970', 'wikidata': 'https://www.wikidata.org/wiki/Q169342', 'display_name': 'Retina', 'level': 2, 'score': 0.9086665}, {'id': 'https://openalex.org/C2778534260', 'wikidata': 'https://www.wikidata.org/wiki/Q218706', 'display_name': 'Erythropoietin', 'level': 2, 'score': 0.785338}, {'id': 'https://openalex.org/C2780827179', 'wikidata': 'https://www.wikidata.org/wiki/Q422001', 'display_name': 'Retinal', 'level': 2, 'score': 0.7606364}, {'id': 'https://openalex.org/C196795494', 'wikidata': 'https://www.wikidata.org/wiki/Q1624817', 'display_name': 'TUNEL assay', 'level': 3, 'score': 0.7158983}, {'id': 'https://openalex.org/C2777506830', 'wikidata': 'https://www.wikidata.org/wiki/Q4113799', 'display_name': 'Inner nuclear layer', 'level': 3, 'score': 0.7011053}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.50925815}, {'id': 'https://openalex.org/C118487528', 'wikidata': 'https://www.wikidata.org/wiki/Q161437', 'display_name': 'Ophthalmology', 'level': 1, 'score': 0.47179168}, {'id': 'https://openalex.org/C2781040256', 'wikidata': 'https://www.wikidata.org/wiki/Q7316761', 'display_name': 'Retinal degeneration', 'level': 3, 'score': 0.41451484}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.4000808}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.36683446}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.3445798}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.30413413}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.27315328}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.2686884}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.10903618}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D004921', 'descriptor_name': 'Erythropoietin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D012160', 'descriptor_name': 'Retina', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D012162', 'descriptor_name': 'Retinal Degeneration', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001813', 'descriptor_name': 'Blood-Retinal Barrier', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004921', 'descriptor_name': 'Erythropoietin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008027', 'descriptor_name': 'Light', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008027', 'descriptor_name': 'Light', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020419', 'descriptor_name': 'Photoreceptor Cells, Vertebrate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020419', 'descriptor_name': 'Photoreceptor Cells, Vertebrate', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012160', 'descriptor_name': 'Retina', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012162', 'descriptor_name': 'Retinal Degeneration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012162', 'descriptor_name': 'Retinal Degeneration', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D012162', 'descriptor_name': 'Retinal Degeneration', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15938809', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4220673663', 'https://openalex.org/W2393940952', 'https://openalex.org/W2382156931', 'https://openalex.org/W2370987809', 'https://openalex.org/W2360978323', 'https://openalex.org/W2357661373', 'https://openalex.org/W2306297087', 'https://openalex.org/W2243826416', 'https://openalex.org/W2020881964', 'https://openalex.org/W2012335077'], 'abstract_inverted_index': {'To': [0], 'study': [1], 'whether': [2], 'recombinant': [3], 'human': [4], 'erythropoietin': [5], 'can': [6, 306], 'pass': [7, 307], 'through': [8, 308], 'mice': [9, 32, 44, 310, 319], 'blood-retina': [10, 311], 'barrier': [11, 312], 'and': [12, 60, 68, 148, 157, 170, 177, 184, 197, 214, 218, 293, 313], 'the': [13, 21, 25, 53, 122, 137, 143, 151, 154, 165, 168, 178, 187, 190, 235, 243, 257, 266, 281, 290, 309], 'protective': [14], 'role': [15], 'in': [16, 19, 29, 57, 79, 101, 121, 161, 205, 216, 224, 246, 280, 296], 'light-induced': [17, 50], 'damage': [18, 204], 'retina.After': [20], 'injection': [22], 'of': [23, 27, 55, 76, 119, 259, 286], 'rHEPO,': [24], 'content': [26], 'rHEPO': [28, 58, 78, 120, 134, 199, 291, 314, 321], '24': [30, 42], 'BALB/c': [31, 43], 'retina': [33, 56, 123, 155], 'was': [34, 63, 84, 269], 'examined': [35], 'by': [36, 108, 232], 'enzyme': [37], 'linked': [38], 'immunosorbent': [39], 'assay': [40], '(ELISA).': [41], 'were': [45, 112, 159, 173, 230, 242, 262, 278, 300], 'used': [46, 324], 'to': [47, 325], 'establish': [48], 'a': [49, 202, 273], 'damaged': [51, 174], 'model,': [52], 'difference': [54], 'group': [59, 62, 200, 292, 295], 'control': [61, 294], 'compared': [64], 'using': [65], 'light': [66, 141, 239], 'microscope': [67], 'TdT-mediated': [69], 'dUTP': [70], 'nick': [71], 'end': [72], 'labeling': [73], '(TUNEL).The': [74], 'amount': [75], 'retinal': [77, 104, 191, 225, 328], 'four': [80], 'deferent': [81], 'time': [82, 207], 'points': [83, 208], '(0.68': [85], '+/-': [86, 90, 94, 98], '0.24)': [87, 95], 'mU,': [88, 92, 96], '(1.87': [89], '0.37)': [91], '(0.96': [93], '(0.47': [97], '0.13)': [99], 'mU': [100], '100': [102], 'microg': [103], 'total': [105], 'protein': [106], 'respectively': [107], 'ELISA': [109], 'assay,': [110], 'there': [111, 241], 'statistical': [113, 301], 'significances': [114], 'among': [115], 'groups.': [116], 'The': [117, 227], 'density': [118], 'reached': [124], 'its': [125], 'peak': [126], 'at': [127, 136, 265], '4th': [128], 'hour': [129, 139, 153, 167, 237, 256], 'after': [130, 140, 238], 'injection.': [131], 'Histology': [132], 'analysis:': [133], 'group,': [135], '12th': [138, 236], 'exposure': [142], 'inner': [144, 169, 217], 'segment': [145], 'became': [146, 182, 195], 'condensed': [147], 'disorganized.': [149], 'At': [150, 164, 234, 254], '36th': [152, 255], 'disorganized': [156, 213], 'vesiculated': [158, 215], 'seen': [160], 'outer': [162, 171, 179, 192, 210, 219, 247, 251, 282, 297], 'segments.': [163, 220], '72nd': [166, 267], 'segments': [172], 'more': [175], 'seriously': [176], 'nuclear': [180, 193, 211, 248, 283, 298], 'layer': [181, 194, 212, 249, 299], 'thinner': [183, 196], 'denser.': [185], 'On': [186], '7th': [188], 'day,': [189], 'condenses.': [198], 'showed': [201], 'minimal': [203], 'every': [206], 'but': [209], 'No': [221], 'obvious': [222], 'changes': [223], 'thickness.': [226], 'apoptotic': [228, 244, 260, 276, 287], 'cells': [229, 245, 261, 277, 288], 'detected': [231], 'TUNEL.': [233], 'exposure,': [240], 'near': [250], 'plexiform': [252], 'layer.': [253, 284], 'numbers': [258], 'increased,': [263], 'however': [264], 'it': [268], 'decreased': [270], 'obviously,': [271], 'only': [272], 'few': [274], 'scattering': [275], 'revealed': [279], 'Numbers': [285], 'between': [289], 'significance': [302], '(P': [303], '<': [304], '0.01).rHEPO': [305], 'has': [315], 'neuroprotective': [316], 'effect': [317], 'on': [318], 'retina.': [320], 'may': [322], 'be': [323], 'treat': [326], 'degenerative': [327], 'diseases.': [329]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2360978323', 'counts_by_year': [], 'updated_date': '2024-12-08T16:50:56.233700', 'created_date': '2016-06-24'}